SN-38, a metabolite of the camptothecin derivative CPT-11, potentiates the cytotoxic effect of radiation in human colon adenocarcinoma cells grown as spheroids

Author:

Omura Motoko,Torigoe Soichiro,Kubota Nobuo

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Oncology,Hematology

Reference22 articles.

1. Inhibition of potentially lethal DNA damage repair in human tumor cells by β-lapachone, an activator of topoisomerase I;Boothman;Cancer Res.,1989

2. Posttreatment exposure to camptothecin enhances the lethal effects of X-rays on radioresistant human malignant melanoma cells;Boothman;Int. J. Radiat. Oncol. Biol. Phys.,1992

3. Chemosensitivity testing in V79 spheroids: drug delivery and cellular microenvironment;Durand;J. Natl. Cancer Inst.,1986

4. DNA damaging and cell cycle effects of the topoisomerase I poison camptothecin in irradiated human cells;Falk;Int. J. Radiat. Biol.,1992

5. A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer;Fukuoka;J. Clin. Oncol.,1992

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