TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck

Author:

Alsner Jan,Sørensen Susanne Berg,Overgaard Jens

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Oncology,Hematology

Reference37 articles.

1. High incidence of p53 alterations (mutation, deletion, over-expression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein over-expression in normal epithelium and in early non-invasive lesions;Ahomadegbe;Oncogene,1995

2. Interaction between potential doubling time and TP53 mutation: predicting radiotherapy outcome in squamous cell carcinoma of the head and neck;Alsner;Int J Radiat Oncol Biol Phys,2001

3. The value of pre-treatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: a multicenter analysis;Begg;Radiother Oncol,1999

4. Tumor radiosensitivity (SF2) is a prognostic factor for local control in head and neck cancers;Bjørk-Eriksson;Int J Radiat Oncol Biol Phys,2000

5. Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases;Blencowe;Trends Biochem Sci,2000

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