The characterization of γH2AX and p53 as biomarkers of genotoxic stress in a rainbow trout (Oncorhynchus mykiss) brain cell line

Author:

Hamilton Mark E.,Bols Niels C.,Duncker Bernard P.

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Elsevier BV

Subject

General Medicine,General Chemistry,Environmental Chemistry,Environmental Engineering,Pollution,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference74 articles.

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2. Effects of chronic exposure to benzalkonium chloride in Oncorhynchus mykiss: cholinergic neurotoxicity, oxidative stress, peroxidative damage and genotoxicity;Antunes;Environ. Toxicol. Pharmacol.,2016

3. 4-Nitroquinoline 1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species;Arima;Toxicol. Sci.,2006

4. Use of the γH2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines;Audebert;Toxicol. Lett.,2010

5. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks;Banáth;Cancer Res.,2003

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