Tamoxifen-induced hepatotoxicity via lipid accumulation and inflammation in zebrafish

Author:

Yu Qinwei,Huo Jingting,Zhang YunORCID,Liu Kechun,Cai Yu,Xiang Ting,Jiang ZhenzhouORCID,Zhang Luyong

Funder

National Natural Science Foundation of China

Major Scientific and Technological Special Project for Significant New Drugs

Specific Fund for Public Interest Research of Traditional Chinese Medicine, Ministry of finance

“Double First-Class” University project

Publisher

Elsevier BV

Subject

General Medicine,General Chemistry,Environmental Chemistry,Environmental Engineering,Pollution,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference49 articles.

1. Long-term adjuvant tamoxifen therapy and decreases in contralateral breast cancer;Abderrahman;JAMA oncology,2017

2. Dietary lipid during late-pregnancy and early-lactation to manipulate metabolic and inflammatory gene network expression in dairy cattle liver with a focus on PPARs;Akbar;Gene Regul. Syst. Biol.,2013

3. Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish;Archer;Dev. Dynam. : an official publication of the American Association of Anatomists,2008

4. The biology of cachectin/TNF--a primary mediator of the host response;Beutler;Annu. Rev. Immunol.,1989

5. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: preliminary results of the Italian Tamoxifen Anastrozole Trial;Boccardo;J. Clin. Oncol. : official journal of the American Society of Clinical Oncology,2005

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