An improved synthesis of (20R,22R)-cholest-5-ene-3β,20,22-triol, an intermediate in steroid hormone formation and an activator of nuclear orphan receptor LXRα-Reference-Cited by-同舟云学术

An improved synthesis of (20R,22R)-cholest-5-ene-3β,20,22-triol, an intermediate in steroid hormone formation and an activator of nuclear orphan receptor LXRα

Published:1999-06 Issue:6 Volume:64 Page:385-395
ISSN:0039-128X
Container-title:Steroids
language:en
Short-container-title:Steroids

Author:

Ruan Benfang,Wilson William K.,Schroepfer George J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference30 articles.

1. Mass spectrometric study of the enzymatic conversion of cholesterol to (22R)-22-hydroxycholesterol, (20R,22R)-20,22-dihydroxycholesterol, and pregnenolone, and of (22R)-22-hydroxycholesterol to the glycol and pregnenolone in bovine adrenocortical preparations. Mode of oxygen incorporation;Burstein;J Biol Chem,1975

2. Cholesterol side-chain cleavage by mitochondria from the human placenta. Studies using hydroxycholesterols as substrates;Tuckey;J Steroid Biochem Mol Biol,1992

3. Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome P-450scc system;Sugano;J Biochem,1996

4. The isolation of crystalline 22R-hydroxycholesterol and 20α,22R-dihydroxycholesterol from bovine adrenals;Dixon;Biochem Biophys Res Commun,1970

5. An oxysterol signalling pathway mediated by the nuclear receptor LXRα;Janowski;Nature,1996

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