Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum-Reference-Cited by-同舟云学术

Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum

Published:2015-10 Issue:10 Volume:2 Page:1507-1512
ISSN:2352-3964
Container-title:EBioMedicine
language:en
Short-container-title:EBioMedicine

Author:

Devereux Graham,Fraser-Pitt Douglas,Robertson Jennifer,Devlin Edward,Mercer Derry,O'Neil Deborah

Funder

Scottish Enterprise Encompass Kick Start

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference27 articles.

1. Antibiotic treatment of CF lung disease: from bench to bedside;Bals;J. Cyst. Fibros.,2011

2. Cysteamine: an old drug with new potential;Besouw;Drug Discov. Today,2013

3. The expanding armamentarium of drugs to aid sputum clearance: how should they be used to optimize care?;Bilton;Curr. Opin. Pulm. Med.,2014

4. Whole-genome sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study;Bryant;Lancet,2013

5. Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis;Charrier;Orphanet J. Rare Dis.,2014

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multiple antimicrobial and immune-modulating activities of cysteamine in infectious diseases;Biomedicine & Pharmacotherapy;2024-09

2. Therapy of Mycobacterium abscessus Infections in Solid Organ Transplant Patients;Microorganisms;2024-03-16

3. Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection;Biochemical and Biophysical Research Communications;2023-10

4. Cysteamine/Cystamine Exert Anti-Mycobacterium abscessus Activity Alone or in Combination with Amikacin;International Journal of Molecular Sciences;2023-01-07

5. Pseudomonas aeruginosa utilizes the host-derived polyamine spermidine to facilitate antimicrobial tolerance;JCI Insight;2022-11-22