Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference53 articles.
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1. Genetic evidence for efficacy of targeting IL-2, IL-6 and TYK2 signalling in the prevention of type 1 diabetes: a Mendelian randomisation study;Diabetologia;2024-09-13
2. Exploring the effect of deucravacitinib in patients with palmoplantar pustular psoriasis;Journal of Dermatological Treatment;2024-09-10
3. Identification of diagnostic genes and drug prediction in metabolic syndrome-associated rheumatoid arthritis by integrated bioinformatics analysis, machine learning, and molecular docking;Frontiers in Immunology;2024-07-29
4. Assessing the causal relationship between obesity and hypothyroidism using Mendelian randomization;Journal of Investigative Medicine;2024-07-24
5. Large-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults;Nature Communications;2024-07-15
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