Mathematical modeling of the early modeled CA-125 longitudinal kinetics (KELIM-PARP) as a pragmatic indicator of rucaparib efficacy in patients with recurrent ovarian carcinoma in ARIEL2 & STUDY 10

Author:

Colomban OlivierORCID,Swisher Elizabeth M.,Kristeleit Rebecca,McNeish Iain,Shapira-Frommer Ronnie,Goble Sandra,Lin Kevin K.,Maloney Lara,Freyer Gilles,You Benoit

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference38 articles.

1. The systemic treatment of recurrent ovarian cancer revisited;Baert;Ann Oncol,2021

2. ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease;Colombo;Int J Gynecol Cancer,2019

3. PARP inhibitors in the management of ovarian cancer: ASCO guideline;Tew;J Clin Oncol,2020

4. Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial;Swisher;Lancet Oncol,2017

5. Efficacy and safety of olaparib monotherapy in germline BRCA 1/2 mutation carriers with advanced ovarian cancer and three or more lines of prior therapy;Domchek;Gynecol Oncol,2016

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