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Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation

  • Published:2017-12 Issue: Volume:26 Page:112-125
  • ISSN:2352-3964
  • Container-title:EBioMedicine
  • language:en
  • Short-container-title:EBioMedicine

Author:

Nitulescu Ioana I.,Meyer Sara C.,Wen Qiang Jeremy,Crispino John D.,Lemieux Madeleine E.,Levine Ross L.,Pelish Henry E.,Shair Matthew D.

Funder

Leukemia and Lymphoma Society

Starr Cancer Consortium

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference87 articles.

1. The Mediator complex: a central integrator of transcription;Allen;Nat. Rev. Mol. Cell Biol.,2015

2. p91 STAT1 activation in interleukin-3-stimulated primary acute myeloid leukemia cells;Aronica;Oncogene,1996

3. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response;Bancerek;Immunity,2013

4. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders;Baxter;Lancet,2005

5. Genomic landscape of megakaryopoiesis and platelet function defects;Bianchi;Blood,2016
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