IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

Author:

Weng Shih-Yen,Wang Xiaoyu,Vijayan Santosh,Tang Yilang,Kim Yong Ook,Padberg Kornelius,Regen Tommy,Molokanova Olena,Chen Tao,Bopp Tobias,Schild Hansjörg,Brombacher Frank,Crosby Jeff R.,McCaleb Michael L.,Waisman Ari,Bockamp Ernesto,Schuppan Detlef

Funder

ERC

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference57 articles.

1. Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages;Barron;Am. J. Physiol. Gastrointest. Liver Physiol.,2011

2. IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages;Bhattacharjee;Free Radic. Biol. Med.,2013

3. Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis;Borthwick;Mucosal Immunol.,2016

4. Phosphorothioate oligodeoxynucleotides distribute similarly in class A scavenger receptor knockout and wild-type mice;Butler;J. Pharmacol. Exp. Ther.,2000

5. Neutrophil function in chronic liver disease;Campbell;Clin. Exp. Immunol.,1981

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