Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank-Reference-Cited by-同舟云学术

Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank

Published:2019-07 Issue: Volume:45 Page:487-494
ISSN:2352-3964
Container-title:EBioMedicine
language:en
Short-container-title:EBioMedicine

Author:

Wang Qi,Wang Yunzhang,Lehto Kelli,Pedersen Nancy L.,Williams Dylan M.,Hägg Sara

Funder

China Scholarship Council

National Natural Science Foundation of China

Karolinska Institutet Delfinansiering

Loo and Hans Osterman Foundation

Foundation for Geriatric Diseases

Magnus Bergwall foundation

Foundation for Gamla Tjänarinnor

Karolinska Institutet

Swedish Research Council

Swedish Council for Working Life and Social Research

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference46 articles.

1. Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study;Benn;BMJ,2017

2. Effects of statins on all-cause mortality at different low-density-lipoprotein cholesterol levels in Asian patients with type 2 diabetes;Chen;Curr Med Res Opin,2018

3. Association of lipid fractions with risks for coronary artery disease and diabetes;White;JAMA Cardiol,2016

4. LDL biochemical modifications: a link between atherosclerosis and aging;Alique;Food Nutr Res,2015

5. Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials;Fulcher;Lancet,2015

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