Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration

Author:

Olney Nicholas T.1,Ong Elise1,Goh Sheng-Yang M.1,Bajorek Lynn1,Dever Reilly1,Staffaroni Adam M.1,Cobigo Yann1,Bock Meredith1,Chiang Kevin1,Ljubenkov Peter1,Kornak John1,Heuer Hilary W.1,Wang Ping1,Rascovsky Katya2,Wolf Amelia1,Appleby Brian3,Bove Jessica2,Bordelon Yvette4,Brannelly Patrick5,Brushaber Danielle6,Caso Christine7,Coppola Giovanni4,Dickerson Bradford C.8,Dickinson Susan9,Domoto-Reilly Kimiko7,Faber Kelly10,Ferrall Jessica11,Fields Julie12,Fishman Ann13,Fong Jamie1,Foroud Tatiana10,Forsberg Leah K.12,Gearhart Debra J.12,Ghazanfari Behnaz14,Ghoshal Nupur1516,Goldman Jill1718,Graff-Radford Jonathan12,Graff-Radford Neill R.19,Grant Ian20,Grossman Murray2,Haley Dana19,Hsiung Gingyuek21,Huey Edward D.1718,Irwin David J.2,Jones David T.12,Kantarci Kejal12,Karydas Anna M.1,Kaufer Daniel11,Kerwin Diana2223,Knopman David S.12,Kramer Joel H.1,Kraft Ruth12,Kremers Walter6,Kukull Walter24,Lapid Maria I.12,Litvan Irene25,Mackenzie Ian R.26,Maldonado Miranda4,Manoochehri Masood1718,McGinnis Scott M.8,McKinley Emily C.27,Mendez Mario F.4,Miller Bruce L.1,Onyike Chiadi13,Pantelyat Alex28,Pearlman Rodney29,Petrucelli Len19,Potter Madeleine10,Rademakers Rosa19,Ramos Eliana M.4,Rankin Katherine P.1,Roberson Erik D.27,Rogalski Emily20,Sengdy Pheth21,Shaw Leslie M.2,Syrjanen Jeremy6,Tartaglia M. Carmela1430,Tatton Nadine9,Taylor Joanne1,Toga Arthur31,Trojanowski John Q.2,Weintraub Sandra20,Wong Bonnie8,Wszolek Zbigniew19,Boxer Adam L.1,Boeve Brad F.12,Rosen Howard J.1,

Affiliation:

1. Department of Neurology; Memory and Aging Center, University of California, San Francisco; San Francisco CA USA

2. Department of Neurology; Perelman School of Medicine, University of Pennsylvania; Philadelphia PA USA

3. Department of Neurology; Case Western Reserve University; Cleveland OH USA

4. Department of Neurology; University of California, Los Angeles; Los Angeles CA USA

5. Tau Consortium; Rainwater Charitable Foundation; Fort Worth TX USA

6. Department of Health Sciences Research; Mayo Clinic; Rochester MN USA

7. Department of Neurology; University of Washington; Seattle WA USA

8. Department of Neurology; Frontotemporal Disorders Unit; Massachusetts General Hospital; Harvard Medical School; Boston MA USA

9. Association for Frontotemporal Degeneration; Radnor PA USA

10. National Centralized Repository for Alzheimer's Disease and Related Disorders (NCRAD); Indiana University; Indianapolis IN USA

11. Department of Neurology; University of North Carolina; Chapel Hill NC USA

12. Department of Neurology; Mayo Clinic; Rochester MN USA

13. Department of Psychiatry and Behavioral Sciences; School of Medicine; Johns Hopkins University; Baltimore MD USA

14. Division of Neurology; Department of Medicine; University of Toronto; Toronto Ontario Canada

15. Department of Psychiatry; Washington University; St. Louis MO USA

16. Department of Neurology; Washington University; St. Louis MO USA

17. Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Columbia University; New York NY USA

18. Department of Neurology; Columbia University; New York NY USA

19. Department of Neurology; Mayo Clinic; Jacksonville FL USA

20. Department of Neurology; Feinberg School of Medicine; Northwestern University; Chicago IL USA

21. Division of Neurology; Department of Medicine; University of British Columbia; Vancouver British Columbia Canada

22. Department of Neurology and Neurotherapeutics; Center for Alzheimer’s and Neurodegenerative Diseases; The University of Texas; Southwestern Medical Center at Dallas; Dallas TX USA

23. Department of Internal Medicine; The University of Texas; Southwestern Medical Center at Dallas; Dallas TX USA

24. National Alzheimer Coordinating Center (NACC); University of Washington; Seattle WA USA

25. Department of Neurosciences, Parkinson and Other Movement Disorders Center; University of California, San Diego; San Diego CA USA

26. Department of Pathology and Laboratory Medicine; University of British Columbia; Vancouver BC Canada

27. Department of Neurology; Alzheimer’s Disease Center; University of Alabama at Birmingham; Birmingham AL USA

28. Department of Neurology; School of Medicine; Johns Hopkins University; Baltimore MD USA

29. The Bluefield Project; San Francisco CA USA

30. Tanz Centre for Research in Neurodegenerative Diseases; University of Toronto; Toronto ON Canada

31. Laboratory of Neuroimaging (LONI); University of Southern California; Los Angeles CA USA

Funder

Centers for Disease Control

Biogen

Alector

NIH

Mayo Clinic

Little Family Foundation

AbbVie

Bristol-Myers Squibb

C2N Diagnostics

Tau Research Consortium

Association for Frontotemporal Degeneration

Corticobasal Degeneration Solutions

Alzheimer's Drug Discovery Foundation

Alzheimer's Association

Avid

BMS

C2N

Cortice

Eli Lilly

Forum

Genentech

Janssen

Novartis

Pfizer

Roche

TauRx

Avid Radiopharmaceuticals

Janssen Pharmaceuticals

Bristol Myers Squibb

Janssen Immunotherapy

Wyeth

SNIFF

Tau Consortium

Association for Frontotemporal Dementia

HDSA

New York State Department of Health

Lilly

Piramal

AstraZeneca

Canadian Institutes of Health Research

Alzheimer Society of British Columbia

BrightFocus Foundation

Penn Institute on Aging

Minnesota Partnership for Biotechnology and Medical Genomics

Abbvie

Janssen Research & Development

Navidea Biopharmaceuticals

HRSA

Bryan Family Foundation

Eisai

UCSF

University of Southern California

DOD

Parkinson Study Group

Parkinson Foundation

Michael J Fox Foundation

AVID Pharmaceuticals

Allon Therapeutics Inc

Eisai Inc.

Eli Lilly and Co.

Medivation

Merck

TauRx Therapeutics

NIA

CIHR

Jane Tanger Black

Biogen, Inc

Larry L. Hillblom foundation

Mayo Clinic Center for Regenerative Medicine

National Institutes of Health

Larry L. Hillblom Foundation

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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