Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease

Author:

Morgen Katrin1,Ramirez Alfredo23,Frölich Lutz1,Tost Heike1,Plichta Michael M.1,Kölsch Heike3,Rakebrandt Fabian4,Rienhoff Otto4,Jessen Frank25,Peters Oliver6,Jahn Holger7,Luckhaus Christian8,Hüll Michael9,Gertz Hermann‐Josef10,Schröder Johannes11,Hampel Harald12,Teipel Stefan J.1314,Pantel Johannes15,Heuser Isabella6,Wiltfang Jens16,Rüther Eckart17,Kornhuber Johannes5,Maier Wolfgang218,Meyer‐Lindenberg Andreas1

Affiliation:

1. Central Institute of Mental HealthMedical Faculty Mannheim/Heidelberg UniversityHeidelbergGermany

2. Department of Psychiatry and PsychotherapyUniversity of BonnBonnGermany

3. Institute of Human GeneticsUniversity of BonnBonnGermany

4. Department of Medical InformaticsUniversity of GöttingenGöttingenGermany

5. Friedrich Alexander University of Erlangen‐NurembergErlangenGermany

6. Department of Psychiatry and PsychotherapyCharité BerlinBerlinGermany

7. Department of Psychiatry and PsychotherapyUniversity of HamburgHamburgGermany

8. Department of Psychiatry and PsychotherapyUniversity of DüsseldorfDüsseldorfGermany

9. Department of Psychiatry and PsychotherapyUniversity of FreiburgFreiburgGermany

10. Department of Psychiatry and PsychotherapyUniversity of LeipzigLeipzigGermany

11. Department of Psychiatry and PsychotherapyUniversity of HeidelbergHeidelbergGermany

12. Département de Neurologie Institut de la Mémoire et de la Maladie d'AlzheimerUniversité Pierre et Marie Curie Hôpital de la SalpétriéreParisFrance

13. Department of Psychiatry and PsychotherapyUniversity of RostockRostockGermany

14. German Center for Neurodegenerative Diseases (DZNE)RostockGermany

15. Institute of General PracticeUniversity of FrankfurtFrankfurtGermany

16. Department of Psychiatry and PsychotherapyUniversity of EssenEssenGermany

17. Department of Psychiatry and PsychotherapyUniversity of GöttingenGöttingenGermany

18. German Center for Neurodegenerative DiseasesBonnGermany

Funder

German Federal Ministry of Education and Research

Kompetenznetz Demenzen

Katharina Hardt Foundation

BMBF

German Research Foundation

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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