Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

Author:

Roher Alex E.1,Esh Chera L.1,Kokjohn Tyler A.12,Castaño Eduardo M.3,Van Vickle Gregory D.1,Kalback Walter M.1,Patton R. Lyle1,Luehrs Dean C.1,Daugs Ian D.1,Kuo Yu‐Min4,Emmerling Mark R.5,Soares Holly5,Quinn Joseph F.6,Kaye Jeffrey6,Connor Donald J.7,Silverberg Nina B.7,Adler Charles H.8,Seward James D.7,Beach Thomas G.9,Sabbagh Marwan N.7

Affiliation:

1. The Longtine Center for Molecular Biology and GeneticsSun Health Research InstituteSun CityAZUSA

2. Department of MicrobiologyMidwestern UniversityGlendaleAZUSA

3. Fundacion Instituto LeloirBuenos AiresArgentina

4. Department of Cell Biology and AnatomyNational Cheng Kung UniversityTainanTaiwan

5. Pfizer Global Research and DevelopmentGrotonCTUSA

6. Oregon Health and Science UniversityDepartment of NeurologyPortlandORUSA

7. Cleo Roberts Center for Clinical ResearchSun Health Research InstituteSun CityAZUSA

8. Department of NeurologyMayo ClinicScottsdaleAZUSA

9. W. H. Civin Laboratory of NeuropathologySun Health Research InstituteSun CityAZUSA

Funder

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Reference76 articles.

1. O.Hansson H.Zetterberg E.Vanmechelen H.Vanderstichele U.Andreasson E.Londos et al.Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol Aging2008 Oct 25[Epublication ahead of print]

2. Elevated Aβ42 in Skeletal Muscle of Alzheimer Disease Patients Suggests Peripheral Alterations of AβPP Metabolism

3. Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets;Li Q.X.;Lab Invest,1998

4. Disruption of pathologic amyloid beta‐protein fibril assembly on the surface of cultured human cerebrovascular smooth muscle cells;Van Nostrand W.E.;Amyloid,2001

5. Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

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