Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease

Author:

Chen Zhicheng1,Mengel David1,Keshavan Ashvini2,Rissman Robert A.34,Billinton Andrew5,Perkinton Michael5,Percival‐Alwyn Jennifer5,Schultz Aaron6,Properzi Michael6,Johnson Keith6,Selkoe Dennis J.1,Sperling Reisa A.1,Patel Purvish7,Zetterberg Henrik28910,Galasko Douglas3,Schott Jonathan M.2,Walsh Dominic M.12

Affiliation:

1. Laboratory for Neurodegenerative ResearchAnn Romney Center for Neurologic DiseasesBrigham and Women's Hospital and Harvard Medical SchoolBostonMAUSA

2. Department of Neurodegenerative DiseaseUCL Institute of NeurologyQueen SquareLondonEngland

3. Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

4. VA San Diego Healthcare SystemLa JollaCAUSA

5. AstraZeneca Neuroscience Innovative MedicinesMedImmune LtdCambridgeEngland

6. Massachusetts General Hospital and Harvard Medical SchoolCharlestownMAUSA

7. Quanterix CorporationLexingtonMAUSA

8. UK Dementia Research Institute at UCLLondonEngland

9. Clinical Neurochemistry LaboratorySahlgrenska University HospitalMölndalSweden

10. Department of Psychiatry and NeurochemistryInstitute of Neuroscience and PhysiologySahlgrenska Academy at the University of GothenburgMölndalSweden

Funder

Medimmune

Leonard Wolfson Experimental Neurology Center

Weston Brain Institute

Wolfson Foundation

German Research Foundation

DFG

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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