Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration

Author:

Alosco Michael L.12,Tripodis Yorghos13,Fritts Nathan G.1,Heslegrave Amanda45,Baugh Christine M.6,Conneely Shannon1,Mariani Megan1,Martin Brett M.17,Frank Samuel8,Mez Jesse12,Stein Thor D.191011,Cantu Robert C.12121314,McKee Ann C.1291011,Shaw Leslie M.15,Trojanowski John Q.15,Blennow Kaj1617,Zetterberg Henrik451617,Stern Robert A.121318

Affiliation:

1. Boston University Alzheimer's Disease Center and Boston University CTE CenterBoston University School of MedicineBostonMAUSA

2. Department of NeurologyBoston University School of MedicineBostonMAUSA

3. Department of BiostatisticsBoston University School of Public HealthBostonMAUSA

4. Department of Molecular NeuroscienceUCL Institute of NeurologyQueen SquareLondonUK

5. UK Dementia Research Institute at UCLLondonUK

6. Interfaculty Initiative in Health PolicyHarvard UniversityBostonMAUSA

7. Data Coordinating CenterBoston University School of Public HealthBostonMAUSA

8. Department of NeurologyHarvard Medical SchoolBostonMAUSA

9. Departments of Pathology and Laboratory MedicineBoston University School of MedicineBostonMAUSA

10. VA Boston Healthcare SystemU.S. Department of Veteran AffairsJamaica PlainMAUSA

11. Department of Veterans Affairs Medical CenterBedfordMAUSA

12. Concussion Legacy FoundationBostonMAUSA

13. Department of NeurosurgeryBoston University School of MedicineBostonMAUSA

14. Department of NeurosurgeryEmerson HospitalConcordMAUSA

15. Center for Neurodegenerative Disease ResearchDepartment of Pathology and Laboratory MedicineUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPAUSA

16. Clinical Neurochemistry LaboratorySahlgrenska University HospitalMölndalSweden

17. Department of Psychiatry and NeurochemistryInstitute of Neuroscience and PhysiologySahlgrenska Academy at the University of GothenburgGothenburgSweden

18. Department of Anatomy and NeurobiologyBoston University School of MedicineBostonMAUSA

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

National Center for Advancing Translational Sciences

NIH

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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