Vascular dysfunction—The disregarded partner of Alzheimer's disease

Author:

Sweeney Melanie D.1,Montagne Axel1,Sagare Abhay P.1,Nation Daniel A.23,Schneider Lon S.345,Chui Helena C.34,Harrington Michael G.6,Pa Judy7,Law Meng38,Wang Danny J. J.7,Jacobs Russell E.1,Doubal Fergus N.9,Ramirez Joel101112,Black Sandra E.13,Nedergaard Maiken1415,Benveniste Helene16,Dichgans Martin17,Iadecola Costantino18,Love Seth19,Bath Philip M.2021,Markus Hugh S.22,Salman Rustam A.9,Allan Stuart M.23,Quinn Terence J.24,Kalaria Rajesh N.25,Werring David J.26,Carare Roxana O.27,Touyz Rhian M.28,Williams Steve C. R.29,Moskowitz Michael A.30,Katusic Zvonimir S.31,Lutz Sarah E.32,Lazarov Orly32,Minshall Richard D.3334,Rehman Jalees3536,Davis Thomas P.37,Wellington Cheryl L.38,González Hector M.39,Yuan Chun40,Lockhart Samuel N.4142,Hughes Timothy M.4142,Chen Christopher L. H.4344,Sachdev Perminder45,O'Brien John T.46,Skoog Ingmar47,Pantoni Leonardo48,Gustafson Deborah R.49,Biessels Geert Jan50,Wallin Anders51,Smith Eric E.52,Mok Vincent5354,Wong Adrian53,Passmore Peter55,Barkof Frederick5657,Muller Majon58,Breteler Monique M. B.5960,Román Gustavo C.61,Hamel Edith62,Seshadri Sudha6364,Gottesman Rebecca F.65,Buchem Mark A.66,Arvanitakis Zoe6768,Schneider Julie A.6768,Drewes Lester R.69,Hachinski Vladimir70,Finch Caleb E.71,Toga Arthur W.37,Wardlaw Joanna M.9,Zlokovic Berislav V.13

Affiliation:

1. Department of Physiology and NeuroscienceZilkha Neurogenetic InstituteKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

2. Department of PsychologyUniversity of Southern CaliforniaLos AngelesCAUSA

3. Alzheimer's Disease Research CenterKeck School of Medicine at the University of Southern CaliforniaLos AngelesCAUSA

4. Department of NeurologyKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

5. Department of Psychiatry and the Behavioral SciencesKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

6. Huntington Medical Research InstitutesPasadenaCAUSA

7. Laboratory of Neuro Imaging (LONI)Stevens Institute for Neuroimaging and InformaticsKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

8. Department of RadiologyKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

9. Neuroimaging Sciences and Brain Research Imaging CenterDivision of Neuroimaging SciencesCenter for Clinical Brain SciencesUK Dementia Research Institute at the University of EdinburghUK

10. LC Campbell Cognitive Neurology Research UnitSunnybrook Research InstituteUniversity of TorontoTorontoONCanada

11. Hurvitz Brain Sciences Research ProgramSunnybrook Research InstituteUniversity of TorontoTorontoONCanada

12. Heart and Stroke Foundation Canadian Partnership for Stroke RecoverySunnybrook Health Sciences CentreUniversity of TorontoTorontoONCanada

13. Department of Medicine (Neurology)Hurvitz Brain Sciences ProgramCanadian Partnership for Stroke Recovery and LC Campbell Cognitive Neurology Research UnitSunnybrook Research InstituteSunnybrook Health Sciences CentreToronto Dementia Research AllianceUniversity of TorontoTorontoCanada

14. Section for Translational NeuroscienceFaculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark

15. Division of Glia Disease and TherapeuticsCenter for Translational NeuromedicineUniversity of Rochester Medical SchoolRochesterNYUSA

16. Department of AnesthesiologyYale School of MedicineNew HavenCTUSA

17. Institute for Stroke and Dementia Research (ISD)Ludwing‐Maximilians‐University MunichMunichGermany

18. Feil Family Brain and Mind Research InstituteWeill Cornell MedicineNew YorkNYUSA

19. Institute of Clinical NeurosciencesUniversity of BristolSchool of MedicineLevel 2 Learning and ResearchSouthmead HospitalBristolUK

20. Stroke Trials UnitDivision of Clinical NeuroscienceUniversity of NottinghamCity Hospital CampusNottinghamUK

21. Stroke, Nottingham University Hospitals NHS TrustCity Hospital CampusNottinghamUK

22. Stroke Research GroupDepartment of Clinical NeurosciencesUniversity of CambridgeCambridge Biomedical CampusCambridgeUK

23. Faculty of Biology, Medicine and HealthDivision of Neuroscience and Experimental PsychologySchool of Biological SciencesUniversity of ManchesterManchesterUK

24. Institute of Cardiovascular and Medical SciencesUniversity of GlasgowGlasgowUK

25. Neurovascular Research GroupInstitute of NeuroscienceNewcastle UniversityNewcastle upon TyneUK

26. Stroke Research CentreDepartment of Brain Repair and RehabilitationUCL Institute of Neurology and the National Hospital for Neurology and NeurosurgeryLondonUK

27. Faculty of MedicineUniversity of SouthamptonSouthamptonUK

28. British Heart Foundation, Glasgow Cardiovascular Research CentreInstitute of Cardiovascular and Medical SciencesUniversity of GlasgowUK

29. Department of NeuroimagingInstitute of PsychiatryPsychology & NeuroscienceKing's College LondonLondonUK

30. Stroke and Neurovascular Regulation LaboratoryDepartments of Radiology and Neurology Harvard Medical SchoolMassachusetts General HospitalBostonMAUSA

31. Department of Anesthesiology and Molecular Pharmacology and Experimental TherapeuticsMayo Clinic College of MedicineRochesterMNUSA

32. Department of Anatomy and Cell BiologyUniversity of Illinois at ChicagoChicagoILUSA

33. Department of AnesthesiologyUniversity of Illinois at ChicagoChicagoILUSA

34. Department of PharmacologyUniversity of Illinois at ChicagoChicagoILUSA

35. Department of PharmacologyThe Center for Lung and Vascular BiologyThe University of Illinois College of MedicineChicagoILUSA

36. Department of MedicineThe Center for Lung and Vascular BiologyThe University of Illinois College of MedicineChicagoILUSA

37. Department of PharmacologyUniversity of ArizonaTucsonAZUSA

38. Department of Pathology and Laboratory MedicineDjavad Mowafaghian Centre for Brain HealthUniversity of British ColumbiaVancouverBritish ColumbiaCanada

39. Department of NeurosciencesUniversity of CaliforniaSan DiegoCAUSA

40. Department of RadiologyUniversity of WashingtonSeattleWAUSA

41. Department of Internal MedicineWake Forest School of MedicineWinston‐SalemNCUSA

42. Alzheimer's Disease Research CenterWake Forest School of MedicineWinston‐SalemNCUSA

43. Department of PharmacologyYong Loo Lin School of MedicineNational University of SingaporeMemory Aging and Cognition CentreNational University Health SystemSingapore

44. Department of Psychological MedicineYong Loo Lin School of MedicineNational University of SingaporeMemory Aging and Cognition CentreNational University Health SystemSingapore

45. Centre for Healthy Brain AgeingSchool of PsychiatryUniversity of New South Wales AustraliaSydneyAustralia

46. Department of PsychiatryUniversity of Cambridge School of Clinical MedicineCambridgeUK

47. Department of Psychiatry and NeurochemistryInstitute of Neuroscience and PhysiologySahlgrenska AcademyUniversity of GothenburgMölndalSweden

48. “L. Sacco” Department of Biomedical and Clinical SciencesUniversity of MilanMilanItaly

49. Department of NeurologyState University of New York‐Downstate Medical CenterBrooklynNYUSA

50. Department of NeurologyBrain Center Rudolf MagnusUniversity Medical Center UtrechtUtrechtThe Netherlands

51. Institute of Neuroscience and PhysiologyUniversity of GothenburgGothenbergSweden

52. Hotchkiss Brain InstituteUniversity of CalgaryAlbertaCanada

53. Department of Medicine and TherapeuticsTherese Pei Fong Chow Research Centre for Prevention of DementiaThe Chinese University of Hong KongHong KongSARChina

54. Gerald Choa Neuroscience CentreLui Che Woo Institute of Innovative MedicineThe Chinese University of Hong KongHong KongSARChina

55. School of MedicineDentistry and Biomedical SciencesQueen's University BelfastBelfastUK

56. Department of Radiology and Nuclear MedicineAmsterdam NeuroscienceVU University Medical CenterAmsterdamThe Netherlands

57. Institutes of Neurology and Healthcare EngineeringUniversity College LondonLondonUK

58. Section of GeriatricsDepartment of Internal MedicineVU University Medical CenterAmsterdamThe Netherlands

59. Department of Population Health SciencesGerman Center for Neurodegenerative Diseases (DZNE)BonnGermany

60. Institute for Medical BiometryInformatics and Epidemiology (IMBIE)Faculty of MedicineUniversity of BonnBonnGermany

61. Department of NeurologyMethodist Neurological InstituteHoustonTXUSA

62. Laboratory of Cerebrovascular ResearchMontreal Neurological InstituteMcGill UniversityMontréalQCCanada

63. The Framingham Heart StudyFraminghamMAUSA

64. Department of NeurologyBoston University School of MedicineBostonMAUSA

65. Departments of Neurology and EpidemiologyJohns Hopkins UniversityBaltimoreMDUSA

66. Department of RadiologyLeiden University Medical CenterLeidenThe Netherlands

67. Department of Neurological SciencesRush University Medical CenterChicagoILUSA

68. Rush Alzheimer's Disease CenterRush University Medical CenterChicagoILUSA

69. Laboratory of Cerebral Vascular BiologyDepartment of Biomedical SciencesUniversity of Minnesota Medical School DuluthDuluthMNUSA

70. Division of NeurologyDepartment of Clinical Neurological SciencesWestern UniversityLondonOntarioCanada

71. Leonard Davis School of GerontologyDornsife CollegeUniversity of Southern CaliforniaLos AngelesCAUSA

Funder

National Institutes of Health

University of Southern California

Laboratory of Neuro Imaging

Alzheimer's Association

Cure Alzheimer's Fund

Foundation Leducq Transatlantic Network

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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