O4–03–02: The gamma secretase inhibitor MK–0752 acutely and significantly reduces CSF Abeta40 concentrations in humans-Reference-Cited by-同舟云学术

O4–03–02: The gamma secretase inhibitor MK–0752 acutely and significantly reduces CSF Abeta40 concentrations in humans

Published:2006-07 Issue:3S_Part_3 Volume:2 Page:
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Rosen Laura B.¹,Stone Julie A.²,Plump Andrew³,Yuan Jinyu³,Harrison Tim⁴,Flynn Mary³,Dallob Aimee³,Matthews Catherine²,Stevenson Donna¹,Schmidt Dennis⁵,Palmieri Theresa⁶,Leibowitz Mark⁶,Jhee Stanford⁶,Ereshefsky Larry⁶,Salomon Ronald⁵,Winchell Greg²,Shearman Mark S.⁴,Murphy M. Gail¹,Gottesdiener Keith M.³

Affiliation:

1. Merck Research LaboratoriesBlue BellPAUSA

2. Merck Research LaboratoriesWest PointPAUSA

3. Merck Research LaboratoriesRahwayNJUSA

4. Merck Research LaboratoriesTerlings ParkUnited Kingdom

5. Vanderbilt UniversityNashvilleTNUSA

6. California Clinical TrialsGlendaleCAUSA

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2006.05.310

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead;European Journal of Medicinal Chemistry;2018-03

2. A Novel Small Molecule Modulator of Amyloid Pathology;Journal of Alzheimer's Disease;2016-06-22

3. Notch Antagonists: Potential Modulators of Cancer and Inflammatory Diseases;Journal of Medicinal Chemistry;2016-04-18

4. Quantitative assessment of Aβ peptide in brain, cerebrospinal fluid and plasma following oral administration of γ-secretase inhibitor MRK-560 in rats;International Journal of Neuroscience;2015-04-28

5. Calcium Channel Blockers, Progression to Dementia, and Effects on Amyloid Beta Peptide Production;Oxidative Medicine and Cellular Longevity;2015