Nasal delivery of chitosan/alginate nanoparticle encapsulated bee ( Apis mellifera ) venom promotes antibody production and viral clearance during porcine reproductive and respiratory syndrome virus infection by modulating T cell related responses

Author:

Lee Jina,Kim Yun-Mi,Kim Ju-Heon,Cho Cheong-Weon,Jeon Jong-Woon,Park Jin-Kyu,Lee Sang-Ho,Jung Bock-Gie,Lee Bong-Joo

Funder

Ministry of Trade, Industry and Energy (MOTIE)

Korea Institute for Advancement of Technology (KIAT)

Publisher

Elsevier BV

Subject

General Veterinary,Immunology

Reference48 articles.

1. Mechanisms of T regulatory cell function;Askenasy;Autoimmun. Rev.,2008

2. Immunohistochemical expression of IL-12, IL-10, IFN-α and IFN-γ in lymphoid organs of porcine reproductive and respiratory syndrome virus-infected pigs;Barranco;Vet. Immunol. Immunopathol.,2012

3. Virological and immunological responses to porcine reproductive and respiratory syndrome virus in a large population of gilts;Batista;Can. J. Vet. Res.,2004

4. Regulatory T cells and infection: a dangerous necessity;Belkaid;Nat. Rev. Immunol.,2007

5. Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen;Borges;Int. Immunopharmacol.,2008

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