Does pharmacokinetic variability influence the efficacy of high-dose methotrexate for the treatment of children with acute lymphoblastic leukemia: What can we learn from small studies?
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology,Hematology
Reference13 articles.
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3. Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia — identification of a relation between concentration and effect;Evans;New England Journal of Medicine,1986
4. Intensive intravenous methotrexate and mercaptopurine treatment of higher-risk non-T, non-B acute lymphoblastic leukemia: a pediatric oncology group study;Camitta;Journal of Clinical Oncology,1994
5. TX clearance is more important for intermediate-risk ALL (Letter);Evans;Journal of Clinical Oncology,1990
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1. High‐dose methotrexate pharmacokinetics and its impact on prognosis of paediatric acute lymphoblastic leukaemia patients: A population pharmacokinetic study;British Journal of Haematology;2024-03-03
2. External evaluation and systematic review of population pharmacokinetic models for high-dose methotrexate in cancer patients;European Journal of Pharmaceutical Sciences;2023-07
3. Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia;Frontiers in Pharmacology;2021-07-13
4. Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients;BMC Cancer;2021-06-20
5. Association of GGH Promoter Methylation Levels with Methotrexate Concentrations in Chinese Children with Acute Lymphoblastic Leukemia;Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy;2020-06-16
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