Idarubicin and idarubicinol are less affected by topoisomerase II-related multidrug resistance than is daunorubicin

Author:

Fukushima Toshihiro,Inoue Hitoshi,Takemura Haruyuki,Kishi Shinzi,Yamauchi Takahiro,Inai Kunihiro,Nakayama Takashi,Imamura Shin,Urasaki Yoshimasa,Nakamura Toru,Ueda Takanori

Publisher

Elsevier BV

Subject

Cancer Research,Oncology,Hematology

Reference28 articles.

1. Synthesis and antitumor activity of 4-demethoxydaunorubicin, 4-demethoxy-7,9-diepidaunorubicin, and their β anomers;Arcamone;Cancer Treat Rep,1976

2. Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia;Berman;Blood,1991

3. Action mechanism of idarubicin (4-demethoxydaunorubicin) as compared with daunorubicin in leukemic cells;Fukushima;Int J Hematol,1993

4. Influence of idarubicinol on the antileukemic effect of idarubicin;Fukushima;Leukemia Res,1994

5. 4-Demethoxydaunorubicin (idarubicin) in combination with 1-β-d-arabinofuranosylcytosine in the treatment of relapsed or refractory acute leukemia;Berman;Cancer Res,1989

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