The effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal and limbic catecholamine neurones in white and black mice antagonism by monoamine oxidase inhibitors

Author:

Bradbury A.J.,Costall B.,Jenner P.G.,Kelly M.E.,Marsden C.D.,Naylor R.J.

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference25 articles.

1. (E)-2-(3',4'-dimentyoxyphenyl)-3-fluoroallylamine: A selective, enzyme-activated inhibitor of type B monoamine oxidase;Bey;J. med. Chem.,1984

2. Repeated administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones;Boyce;Biochem. Pharmac.,1984

3. In albino and pigmented mice MPTP selectively depletes dopamine from striatal and limbic areas but not from hypothalamus;Buckett;Br. J. Pharmac.,1984

4. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by AT-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;Burns,1983

5. The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the monkey and man;Bums;Can. J. Neural. Sci.,1984

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