AKR1C3, a crucial androgenic enzyme in prostate cancer, promotes epithelial-mesenchymal transition and metastasis through activating ERK signaling
Author:
Funder
National Natural Science Foundation of China
United States Army Grant
Publisher
Elsevier BV
Subject
Urology,Oncology
Reference25 articles.
1. Cancer statistics, 2016;Siegel;CA Cancer J Clin,2016
2. Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence;Coutinho;Endocr Relat Cancer,2016
3. Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer;Wako;J Clin Pathol,2008
4. Aldo-keto reductase family 1 member C3 (AKR1C3) is a biomarker and therapeutic target for castration-resistant prostate cancer;Hamid;Mol Med,2013
5. ERG/AKR1C3/AR constitutes a feed-forward loop for AR signaling in prostate cancer cells;Powell;Clin Cancer Res,2015
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