Dupilumab improves nasal polyp burden and asthma control in patients with CRSwNP and AERD

Author:

Laidlaw Tanya M.,Mullol Joaquim,Fan Chunpeng,Zhang Donghui,Amin Nikhil,Khan Asif,Chao Jingdong,Mannent Leda P.

Funder

Sanofi

Regeneron Pharmaceuticals

Sanofi Genzyme

Publisher

Elsevier BV

Subject

Immunology and Allergy

Reference9 articles.

1. European Position Paper on Rhinosinusitis and Nasal Polyps Group. European position paper on rhinosinusitis and nasal polyps 2007;Fokkens;Rhinol Suppl,2007

2. Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes;Macdonald;Proc Natl Acad Sci U S A,2014

3. Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice;Murphy;Proc Natl Acad Sci U S A,2014

4. Dupilumab efficacy and safety in moderate-to-severe uncontrolled asthma;Castro;N Engl J Med,2018

5. Dupilumab efficacy and safety in adult patients with active eosinophilic esophagitis: a randomized double-blind placebo-controlled phase 2 trial. Presented at the 2017 annual scientific meeting of the American College of Gastroenterology;Hirano,2017

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