Silymarin in cancer therapy: Mechanisms of action, protective roles in chemotherapy-induced toxicity, and nanoformulations

Author:

Wang Yin,Yuan Ai-Jun,Wu Yue-Jin,Wu Li-Mei,Zhang Ling

Publisher

Elsevier BV

Subject

Nutrition and Dietetics,Medicine (miscellaneous),Food Science

Reference143 articles.

1. Silymarin ameliorates cisplatin-induced hepatotoxicity in rats: Histopathological and ultrastructural studies;Abdelmeguid;Pakistan Journal of Biological Sciences: PJBS,2010

2. Cytoprotective effect and antioxidant properties of silymarin on cisplatin induced hepatotoxicity in rats: A biochemical and histochemical study;Abouzeinab;International Journal of Cancer Research,2013

3. Antioxidant effect of silymarin on cisplatin-induced renal oxidative stress in rats;Abouzeinab;Journal of Pharmacology and Toxicology,2015

4. Silymarin inhibits the progression of Ehrlich solid tumor via targeting molecular pathways of cell death, proliferation, angiogenesis, and metastasis in female mice;Amer;Molecular Biology Reports,2022

5. Metformin and Silibinin co-loaded PLGA-PEG nanoparticles for effective combination therapy against human breast cancer cells;Amirsaadat;Journal of Drug Delivery Science and Technology,2021

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