New insights into Raf regulation from structural analyses

Author:

Kondo Yasushi,Paul Joseph W.,Subramaniam SriramORCID,Kuriyan John

Funder

NIH

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference58 articles.

1. A comprehensive review on MAPK: a promising therapeutic target in cancer;Braicu;Cancers (Basel),2019

2. RAS proteins and their regulators in human disease;Simanshu;Cell,2017

3. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer;Roberts;Oncogene,2007

4. Regulation of RAF protein kinases in ERK signalling;Lavoie;Nat Rev Mol Cell Biol,2015

5. Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases;Kondo;Science,2019

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