Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling-Reference-Cited by-同舟云学术

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Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling

Published:2019-08 Issue: Volume:57 Page:204-214
ISSN:0959-440X
Container-title:Current Opinion in Structural Biology
language:en
Short-container-title:Current Opinion in Structural Biology

Author:

Kowatsch Christiane,Woolley Rachel E,Kinnebrew Maia,Rohatgi Rajat,Siebold Christian

Funder

Cancer Research UK

Wellcome Trust

National Science Foundation

National Institutes of Health

European Research Council

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference63 articles.

1. Hedgehog signalling;Lee;Development,2016

2. Identification of a palmitic acid-modified form of human Sonic hedgehog;Pepinsky;J Biol Chem,1998

3. Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain;Porter;Cell,1996

4. Cholesterol modification of hedgehog signaling proteins in animal development;Porter;Science,1996

5. Biochemical evidence that patched is the Hedgehog receptor;Marigo;Nature,1996

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1. A novel indole derivative, 2‐{3‐[1‐(benzylsulfonyl)piperidin‐4‐yl]‐2‐methyl‐1H‐indol‐1‐yl}‐1‐(pyrrolidin‐1‐yl)ethenone, suppresses hedgehog signaling and drug‐resistant tumor growth;Archiv der Pharmazie;2024-07-04

2. Increased PTCHD4 expression via m6A modification of PTCHD4 mRNA promotes senescent cell survival;Nucleic Acids Research;2024-05-09

3. Numb positively regulates Hedgehog signaling at the ciliary pocket;Nature Communications;2024-04-25

4. Sonic hedgehog signalling pathway contributes in age-related disorders and Alzheimer's disease;Ageing Research Reviews;2024-04

5. Nile Tilapia (Oreochromis niloticus) Patched1 Mutations Disrupt Cardiovascular Development and Vascular Integrity through Smoothened Signaling;International Journal of Molecular Sciences;2024-03-15

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