Predicting allostery and microbial drug resistance with molecular simulations
Author:
Funder
National Institutes of Health fellowship
The Hartwell Foundation
Knut and Alice Wallenberg Foundation
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference66 articles.
1. Distant and new mutations in CTX-M-1 beta-lactamase affect cefotaxime hydrolysis;Perez-Llarena;Antimicrob Agents Chemother,2011
2. Natural variants of the KPC-2 carbapenemase have evolved increased catalytic efficiency for ceftazidime hydrolysis at the cost of enzyme stability;Mehta;PLoS Pathog,2015
3. Mutations in blaKPC-3 that confer ceftazidime-avibactam resistance encode novel KPC-3 variants that function as extended-spectrum beta-lactamases;Haidar;Antimicrob Agents Chemother,2017
4. A comprehensive, high-resolution map of a gene’s fitness landscape;Firnberg;Mol Biol Evol,2014
5. Deep sequencing of systematic combinatorial libraries reveals beta-lactamase sequence constraints at high resolution;Deng;J Mol Biol,2012
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability;International Journal of Molecular Sciences;2021-03-12
2. Allosteric Regulation at the Crossroads of New Technologies: Multiscale Modeling, Networks, and Machine Learning;Frontiers in Molecular Biosciences;2020-07-09
3. Allosteric drugs and mutations: chances, challenges, and necessity;Current Opinion in Structural Biology;2020-06
4. Residue-Level Allostery Propagates through the Effective Coarse-Grained Hessian;Journal of Chemical Theory and Computation;2020-04-06
5. Residue-Level Allostery Propagates Through the Effective Coarse-Grained Hessian;2019-10-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3