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Drug administration error leading to refractory status epilepticus after intrathecal injection of tranexamic acid: A case report

  • Published:2021-12 Issue: Volume:25 Page:100223
  • ISSN:2405-6030
  • Container-title:Perioperative Care and Operating Room Management
  • language:en
  • Short-container-title:Perioperative Care and Operating Room Management

Author:

Marzouk Mahmoud,Thamlaoui Sabeur,Baffoun Nader,Baccar Kamel,Kaddour Chokri

Publisher

Elsevier BV

Subject

Anesthesiology and Pain Medicine,Medical–Surgical,Critical Care and Intensive Care Medicine,Surgery

Reference15 articles.

1. Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a γ-aminobutyric acidA receptor antagonistic effect;Furtmüller;J Pharmacol Exp Ther,2002

2. High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients;Murkin;Anesth Analg,2010

3. Tranexamic acid: beware of anaesthetic misadventures;Gupta;J Obstet Anaesth Crit Care,2018

4. Accidental intrathecal injection of tranexamic acid;Mahmoud;Case Rep Anesthesiol,2012

5. Inadvertent intrathecal injection of tranexamic acid;Kaabachi;Saudi J Anaesth,2011

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