Permeability of 5-fluorouracil and its prodrugs in Caco-2 cell monolayers: evidence for shift from paracellular to transcellular transport by prodrug formation-Reference-Cited by-同舟云学术

Permeability of 5-fluorouracil and its prodrugs in Caco-2 cell monolayers: evidence for shift from paracellular to transcellular transport by prodrug formation

Published:2009 Issue:1 Volume:19 Page:37-41
ISSN:1773-2247
Container-title:Journal of Drug Delivery Science and Technology
language:en
Short-container-title:Journal of Drug Delivery Science and Technology

Author:

Imoto M.,Azuma H.,Yamamoto I.,Otagiri M.,Imai T.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference20 articles.

1. Fluorouracil: biochemistry and pharmacology;Pinedo;J Clin. Oncol.,1988

2. Clinical pharmacology of 5-fluorouracil;Diasio;Clin Pharmacokinet,1989

3. Fluorouracil therapy in patients with carcinoma of the large bowel: a pharmacokinetic comparison of various rates and routes of administration;Chirstophidis;Clin Pharmacokinet,1978

4. Disposition and metabolism of 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) in humans;Benvenuto;Cancer Res.,1978

5. Clinical relevance of the concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydro-pyrimidine dehydrogenase (DPD) in colorectal cancer;Hiroyasu;Jpn J Clin Oncol,2001

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