DOT-1.1 (DOT1L) deficiency in C. elegans leads to small RNA-dependent gene activation

Author:

Liontis Thomas,Verma Karisma,Grishok AllaORCID

Funder

National Institutes of Health

National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Biochemistry,Biophysics

Reference63 articles.

1. The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription;Cecere;Mol. Cell,2013

2. DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in caenorhabditis elegans;Esse;RNA,2019

3. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure;Jones;PLos Genet.,2008

4. Connecting the DOTs on cell identity;Wille;Front. Cell Dev. Biol.,2022

5. DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation;Godfrey;Nat. Commun.,2019

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