Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reverse transcriptase-Reference-Cited by-同舟云学术

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Rational design and synthesis of phenethyl-5-bromopyridyl thiourea derivatives as potent non-nucleoside inhibitors of HIV reverse transcriptase

Published:1998-10 Issue:10 Volume:6 Page:1789-1797
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Vig Rakesh,Mao Chen,Venkatachalam T.K,Tuel-Ahlgren Lisa,Sudbeck Elise A,Uckun Fatih M

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. Greene, W. C. New Engl. J. Med. 1991, 324, 308.

2. Mitsuya, H.; Yarchoan, R.; Broder, S. Science 1990, 249, 1533.

3. De Clercq, E. J. Acqu. Imm. Defic. Syndr. Res. Hum. Retrovirus 1992, 8, 119.

4. Pauwels, R.; Andries, K.; Desmyter, J.; Schols, D.; Kukla, M. J.; Breslin, H. J.; Raeymaeckers, A.; Van Gelder, J.; Woestenborghs, R.; Heykants, J.; Schellekens, K.; Janssen, M. A. C.; De Clercq, E.; Janssen, P. A. Nature 1990, 343, 470.

5. Tanaka, H.; Baba, M.; Hayakawa, H.; Sakamaki, T.; Miyasaka, T.; Ubasawa, M.; Takashima, H.; Sekiya, K.; Nitta, I.; Shigeta, S.; Walker, R. T.; Balzarini, J.; De Clercq, E. J. Med. Chem. 1991, 34, 349.

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