Galactosamine reduces sandfly gut protease activity through TOR downregulation and increases Lutzomyia susceptibility to Leishmania

Author:

Silva Fernandes Tatiana Lima,Pereira-Filho Adalberto Alves,Nepomuneno Denise Barguil,de Freitas Milagres Tarcísio,Ferreira Malta Luccas Gabriel,D’Ávila Pessoa Grasielle Caldas,Koerich Leonardo BarbosaORCID,Pereira Marcos HorácioORCID,Araujo Ricardo Nascimento,Gontijo Nelder de Figueiredo,Viana Sant'Anna Mauricio RobertoORCID

Funder

INCT-Molecular Entomology

CNPq Brazil

CNPq

Publisher

Elsevier BV

Subject

Insect Science,Molecular Biology,Biochemistry

Reference49 articles.

1. What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity;Abdeladhim;Infect. Genet. Evol.,2014

2. A temporal comparison of sex-aggregation pheromone gland content and dynamics of release in three members of the Lutzomyia longipalpis (Diptera : Psychodidae) species complex;Bandi;PLoS Neglected Trop. Dis.,2017

3. Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies;Bates;Int. J. Parasitol.,2007

4. Trypsin and chymotrypsin-like enzymes of the sandfly Phlebotomus papatasi infected with Leishmania and their possible role in vector competence;Borovsky;Med. Vet. Entomol.,1987

5. TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes;Brandon;Insect Biochem. Mol. Biol.,2008

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