5-HT1A receptor ligands in animal models of anxiety, impulsivity and depression: Multiple mechanisms of action?

Author:

Schreiber Rudy,De Vry Jean

Publisher

Elsevier BV

Subject

Biological Psychiatry,Pharmacology

Reference60 articles.

1. Increased serotonin2 (5-HT2) receptor binding as measured by [3H]-lysergic acid diethylamide ([3H]-LSD) in the blood platelets of depressed patients;Arora;Life Sci.,1989

2. Quantitative autoradiography of 5-HT1A binding in suicide;Arango;Soc. Neurosci. Abstr.,1991

3. Increased number of 5-HT2 receptors in the “learned helplessness” rat;Barone;Eur J Pharmacol,1990

4. Anticonflict and discriminative stimulus effects of the 5-HT1A compounds WY-47,846 and WY-48,723 and the mixed 5-HT1A agonist/5-HT2 antagonist WY- 50,324 in pigeons;Barrett;Drug Dev. Res.,1991

5. Downregulation of brain 5-HT2 receptors underlies anxiolytic effect produced by sustained treatment with gepirone;Benjamin;Soc. Neurosci. Abstr.,1990

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