Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study)-Reference-Cited by-同舟云学术

Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study)

Published:2022-10 Issue:10 Volume:24 Page:2004-2013
ISSN:1098-3600
Container-title:Genetics in Medicine
language:en
Short-container-title:Genetics in Medicine

Author:

Cieuta-Walti Cécile,Cuenca-Royo Aida^ORCID,Langohr Klaus,Rakic Claire,López-Vílchez Ma Ángeles,Lirio Julián,González-Lamuño Leguina Domingo,González Teresa Bermejo,García Jordi García,Roure Maria Rimblas,Aldea-Perona Ana,Forcano Laura,Gomis-Gonzalez Maria,Cés Sebastià Videla,Lacaille Florence,Ravel Aimé,Mircher Clotilde,Walti Hervé,Janel Nathalie,Dairou Julien,Lévy Marilyne,Durand Sophie,Dierssen Mara,Sacco Silvia,Fornell Rafael de la Torre^ORCID,Guerrico Ion Álvarez,Goday Albert,Llop Cristina,Mateus Julián,Matilla Iris,Esther ,Menoyo ,Hernández-Ligero Lorena,Pérez Marta,Pizarro Neus,Principe Alessandro,Cortesi Anna,Gomez Alba,Paredes Noelia,Gomez Cristina,Graell Montserrat,López Pilar,Lozano Rosario,Medrano Constancio,Andrade-Navarro Maria Teresa,Daza Gema,Garcia Sandra,Gayán Ma Luisa,Guerra-Colorado Cristina,Luna Beatriz,Maya Enriqueta,Millan Delia,Reina Macarena,Amigo María Teresa,Fernández José Luís,García-Martínez María,Pérez-Poyato María del Socorro,Pozueta Ana,Tato Emma,Viadero María Teresa,Akkaya Magnolia,Falquero Ségolène,Gambarini Alicia,Akkaya Magnolia,Falquero Ségolène,Gambarini Alicia

Publisher

Elsevier BV

Subject

Genetics (clinical)

Reference15 articles.

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2. Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits;Stringer;Mol Genet Genomic Med,2017

3. Health comorbidities and cognitive abilities across the lifespan in Down syndrome;Startin;J Neurodev Disord,2020

4. Molecular rescue of Dyrk1A overexpression alterations in mice with Fontup® dietary supplement: role of green tea catechins;Gu;Int J Mol Sci Artic,2020

5. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Younes M, Aggett P, et al. Scientific opinion on the safety of green tea catechins;EFSA J,2018

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