Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms
Author:
Funder
Oberlin College Office of Foundation, Government and Corporate Grants
Publisher
Elsevier BV
Subject
Toxicology,General Neuroscience
Reference79 articles.
1. Brain mitochondrial iron accumulates in Huntington’s disease, mediates mitochondrial dysfunction, and can be removed pharmacologically;Agrawal;Free Radic. Biol. Med.,2018
2. Structure and expression of the Huntington’s disease gene: evidence against simple inactivation due to an expanded CAG repeat;Ambrose;Somat. Cell Mol. Genet.,1994
3. Caspase-3-dependent proteolytic cleavage of protein kinase cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl;Anantharam;J Neurosci.,2002
4. Different phenotypic expression in monozygotic twins with Huntington disease;Anca;Am. J. Med. Genet. A,2004
5. Levels of heavy metals in popular cigarette brands and exposure to these metals via smoking;Ashraf;Sci. World J.,2012
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Heavy Metal Interactions with Neuroglia and Gut Microbiota: Implications for Huntington’s Disease;Cells;2024-07-03
2. Sterigmatocystin induced cytotoxicity and disturbed lipid metabolism;Journal of Agriculture and Food Research;2023-12
3. Preliminary study on the E-liquid and aerosol on the neurobehavior of C. elegans;Environment International;2023-09
4. Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity;Nature Communications;2023-07-05
5. Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntington’s Disease Striatal Cells;International Journal of Molecular Sciences;2023-04-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3