Quantum dot conjugated saporin activates microglia and induces selective substantia nigra degeneration

Author:

Landrigan Jeffrey,Dwyer Zach,Beauchamp Sheryl,Rodriguez Ruth,Fortin Teresa,Hayley Shawn

Funder

Canadian Institutes of Health Research

Publisher

Elsevier BV

Subject

Toxicology,General Neuroscience

Reference30 articles.

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2. Cytotoxicity of ribosome-inactivating protein saporin is not mediated through α2-macroglobulin receptor;Bagga;FEBS Lett.,2003

3. The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities;Bagga;J. Biol. Chem.,2003

4. Noninvasive imaging of quantum dots in mice;Ballou;Bioconjug. Chem.,2004

5. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease;Castro-Sánchez;Glia,2018

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