Overexpression of HGF transgene attenuates renal inflammatory mediators, Na+-ATPase activity and hypertension in spontaneously hypertensive rats

Author:

Romero-Vásquez Freddy,Chávez Maribel,Pérez Mariela,Arcaya José L.,García Alberto J.,Rincón Jaimar,Rodríguez-Iturbe Bernardo

Funder

Instituto Venezolano de Investigaciones Científicas, IVIC

Asociación de Amigos del Riñón, Maracaibo, Venezuela

Publisher

Elsevier BV

Subject

Molecular Biology,Molecular Medicine

Reference58 articles.

1. Renal inflammation, autoimmunity and salt-sensitive hypertension;Rodriguez-Iturbe;Clin. Exp. Pharmacol. Physiol.,2011

2. Systemic administration of naked plasmid encoding hepatocyte growth factor ameliorates chronic renal fibrosis in mice;Yang;Gene Ther.,2001

3. Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension;Banday;Am. J. Physiol. Renal Physiol.,2008

4. Na-K-ATPase in nephron segments of rats developing spontaneous hypertension;Garg;Am. J. Physiol.,1985

5. Altered subcellular distribution of Na+, K+‐ATPase in proximal tubules in young spontaneously hypertensive rats;Hinojos;Hypertension,2004

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