Exposure to serum from exclusive heated tobacco product smokers induces mTOR activation and fibrotic features in human cardiac stromal cells

Author:

Picchio Vittorio,Pagano Francesca,Carnevale Roberto,D'Amico Alessandra,Cozzolino Claudia,Floris Erica,Bordin Antonella,Schirone Leonardo,Vecchio Daniele,Saade Wael,Miraldi Fabio,De Falco Elena,Sciarretta Sebastiano,Peruzzi Mariangela,Biondi-Zoccai Giuseppe,Frati Giacomo,Chimenti Isotta

Funder

European Commission

Sapienza Università di Roma

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Elsevier BV

Reference44 articles.

1. Cigarette smoking induces atrial fibrosis in humans via nicotine;Goette;Heart,2007

2. Functional, cellular, and molecular remodeling of the heart under influence of oxidative cigarette tobacco smoke;Kaplan;Oxid. Med. Cell. Longev.,2017

3. The Dynamic Facets of the Cardiac Stroma: From Classical Markers to Omics and Translational Perspectives;Picchio,2022

4. Fibroblasts: origins, definitions, and functions in health and disease;Plikus;Cell,2021

5. The interstitium in cardiac repair: role of the immune–stromal cell interplay;Forte;Nat. Publ. Group,2018

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