Upregulation of Akt signaling enhances femoral fracture healing by accelerating atrophic quadriceps recovery

Author:

Li Guoyuan,Wang Lei,Jiang Yuhang,Kong Xiangdong,Fan Qiming,Ge Shengfang,Hao Yongqiang

Funder

National Natural Science Foundation of China

Key National Basic Research Program of China

Technology Support Project of the Science and Technology Commission of Shanghai

New Cutting-Edge Technology Project of Shen Kang Hospital Development Center of Shanghai

Shanghai Jiao Tong University Cross Research Fund of Medical Engineering

Multicenter Clinical Research Project of Shanghai Jiao Tong University School of Medicine

Publisher

Elsevier BV

Subject

Molecular Biology,Molecular Medicine

Reference51 articles.

1. Timely fracture healing requires optimization of axial fixation stability;Epari;J. Bone Joint Surg. Am.,2007

2. Osteogenic differentiation of periosteal cells during fracture healing;Wang;J. Cell. Physiol.,2017

3. Moderate soft tissue trauma delays new bone formation only in the early phase of fracture healing;Claes;J. Orthop. Res.,2006

4. The biological basis of the bone-muscle inter-relationship in the algorithm of fracture healing;Kaufman;Orthopedics,2008

5. Severe muscle trauma triggers heightened and prolonged local musculoskeletal inflammation and impairs adjacent tibia fracture healing;Hurtgen;J. Musculoskelet. Neuronal Interact.,2016

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