Anti-relapse effect of trametinib on a local minimal residual disease neuroblastoma mouse model

Author:

Togashi YuichiORCID,Tanaka Tomoko,Takemoto Masakazu,Takeuchi Yuki,Higashi Mayumi,Fumino Shigehisa,Tajiri Tatsuro

Funder

Japan Agency for Medical Research and Development

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Elsevier BV

Subject

General Medicine,Pediatrics, Perinatology and Child Health,Surgery

Reference22 articles.

1. Overview and recent advances in the treatment of neuroblastoma;Whittle;Expert Rev Anticancer Ther,2017

2. High-risk neuroblastoma treatment review;Smith;Children (Basel),2018

3. Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo;Yamaguchi;Int J Oncol,2011

4. Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations;Eleveld;Nat Genet,2015

5. Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells;Singh;J Exp Clin Cancer Res,2015

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