Targeting the “undruggable” RAS with biologics
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Publisher
Elsevier
Reference112 articles.
1. Stapled peptides inhibitors: A new window for target drug discovery;Ali;Computational and Structural Biotechnology Journal,2019
2. Site-specific processing of Ras and Rap1 switch I by a MARTX toxin effector domain;Antic;Nature Communications,2015
3. KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe;Bery;Nature Communications,2019
4. A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS;Bery;Nature Communications,2020
5. The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling;Biancucci;Science Signaling,2018
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1. IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers;Journal of Translational Medicine;2024-07-09
2. Probing RAS Function Using Monobody and NanoBiT Technologies;Methods in Molecular Biology;2024
3. Synergy and anti‐cooperativity in allostery: Molecular dynamics study of WT and oncogenic KRAS‐RGL1;Proteins: Structure, Function, and Bioinformatics;2023-12-28
4. Elevated Levels of Mislocalised, Constitutive Ras Signalling Can Drive Quiescence by Uncoupling Cell-Cycle Regulation from Metabolic Homeostasis;Biomolecules;2023-11-06
5. Identification of bioactive compounds from Vaccinium vitis-idaea L. (Lingonberry) as inhibitors for treating KRAS-associated cancer: a computational approach;In Silico Pharmacology;2023-10-30
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