Inhibition of SHP2 as an approach to block RAS-driven cancers
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Elsevier
Reference131 articles.
1. Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop;Aceto;Nature Medicine,2012
2. Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling;Agazie;Molecular and Cellular Biology,2003
3. SHP2 drives adaptive resistance to ERK signaling inhibition in molecularly defined subsets of ERK-dependent tumors;Ahmed;Cell Reports,2019
4. The extended family of protein tyrosine phosphatases;Alonso;Methods in Molecular Biology,2016
5. Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis;Bard-Chapeau;Cancer Cell,2011
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1. Bivalent target-binding bioPROTACs induce potent degradation of oncogenic SHP2;Journal of Biological Chemistry;2024-09
2. Design, Synthesis and Antitumor Activity of a Novel Class of SHP2 Allosteric Inhibitors with a Furanyl Amide-Based Scaffold;Journal of Medicinal Chemistry;2024-07-27
3. SHP2–EGFR States in Dephosphorylation Can Inform Selective SHP2 Inhibitors, Dampening RasGAP Action;The Journal of Physical Chemistry B;2024-05-15
4. Targeting Protein Tyrosine Phosphatases to Improve Cancer Immunotherapies;Cells;2024-01-25
5. Discovery of Novel Substituted Pyridine Carboxamide Derivatives as Potent and Selective Shp2 Allosteric Inhibitors;2024
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