Inhibition of TGF-β pathway reverts extracellular matrix remodeling in T. cruzi -infected cardiac spheroids

Author:

M. Ferrão Patrícia,M. Nisimura Líndice,C. Moreira Otacílio,G. Land Marcelo,Pereira Mirian C.,de Mendonça-Lima Leila,C. Araujo-Jorge Tania,C. Waghabi Mariana,R. Garzoni Luciana

Funder

Fundação Oswaldo Cruz

Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro

Conselho Nacional de Desenvolvimento Científico e Tecnológico

CNPq

Publisher

Elsevier BV

Subject

Cell Biology

Reference40 articles.

1. World Health Organization, Chagas disease (American trypanosomiasis). 〈http://www.who.int/mediacentre/factsheets/fs340/en/〉 (accessed 16 June 2017).

2. Council on Chagas disease of the Interamerican Society of Cardiology. Chagas disease: an overview of clinical and epidemiological aspects;Nunes;J. Am. Coll. Cardiol.,2013

3. Coronary microvascular disease in chronic Chagas cardiomyopathy including an overview on history, pathology, and other proposed pathogenic mechanisms;Rossi;PLoS Negl. Trop. Dis.,2010

4. The TGF-β pathway as an emerging target for Chagas disease therapy;Araújo-Jorge;Clin. Pharmacol. Ther.,2012

5. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling;Bujak;Cardiovasc. Res.,2007

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