TRIM21 inhibits the osteogenic differentiation of mesenchymal stem cells by facilitating K48 ubiquitination-mediated degradation of Akt
Author:
Funder
Southern Medical University
Publisher
Elsevier BV
Subject
Cell Biology
Reference42 articles.
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3. Long-term engraftment of primary bone marrow stromal cells repairs niche damage and improves hematopoietic stem cell transplantation;Abbuehl;Cell Stem Cell,2017
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1. E3 ubiquitin ligases: key regulators of osteogenesis and potential therapeutic targets for bone disorders;Frontiers in Cell and Developmental Biology;2024-08-15
2. K33 only mutant ubiquitin augments bone marrow‐derived dendritic cell‐mediated CTL priming via PI3K‐Akt pathway;Immunology;2024-03-28
3. TRIM21 silencing inhibits the apoptosis and expedites the osteogenic differentiation of dexamethasone‑induced MC3T3‑E1 cells by activating the Keap1/Nrf2 pathway;Experimental and Therapeutic Medicine;2024-03-20
4. Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators;JCI Insight;2023-11-08
5. Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling;Bone Research;2023-10-26
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