Crucial role of HO-1/IRF4-dependent apoptosis induced by panobinostat and lenalidomide in multiple myeloma

Author:

Tang Sishi,Ma Dan,Cheng Bingqing,Fang Qing,Kuang Xingyi,Yu Kunling,Wang Weili,Hu Bo,Wang Jishi

Funder

National Natural Science Foundation of China

International Cooperation Project of Guizhou Province

Social Project of Guizhou Province

Key Discipline of Guizhou Province, Provincial Governor Special Fund of Guizhou Province

Regional Science Foundation of Guizhou Province

Publisher

Elsevier BV

Subject

Cell Biology

Reference35 articles.

1. Multiple myeloma: biology of the disease;Mahindra;Blood Rev.,2010

2. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma;Conery;Elife,2016

3. Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay;Abruzzese;J. Hematol. Oncol.,2016

4. IRF4 addiction in multiple myeloma;Shaffer;Nature,2008

5. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma;Keats;Cancer Cell,2007

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