Suramin Inhibits Gonadotropin Action In Rat Testis: Implications For Treatment Of Advanced Prostate Cancer

Author:

Daugherty Rhett L.1,Cockett Abraham T.K.1,Schoen Susan R.1,Sluss Patrick M.1

Affiliation:

1. From the Department of Urology, University of Rochester, Rochester, New York

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Urology

Reference35 articles.

1. Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells;Coffey;J. Cell Physiol,1987

2. Suramin inhibits binding and degra dation of platelet-derived growth factor in arterial smooth muscle cells but does not interfere with autocrine stimulation of DNA synthesis;Sjolund;Cell Tissue Res.,1989

3. Clinical pharmacokinetics of suramin in patients with HTLV-III/LAV infection;Collins;J. Clin. Pharmacol.,1986

4. Suramin in adrenal cancer: modulation of steroid hormone production, cytotoxicity in vitro, and clinical antitumor effect;LaRocca;J. Clin. Endo. Metab.,1990

5. Use of suramin in treatment of prostatic carcinoma refractory to conventional hormonal manipulations;LaRocca;Urol. Clin. N. Am.,1991

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