Binding of quinidine radically increases the stability and decreases the flexibility of the cytochrome P450 2D6 active site
Author:
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Biochemistry
Reference29 articles.
1. Cytochrome P450: Structure, Mechanism, and Biochemistry,2005
2. Cytochromes P450 and metabolism of xenobiotics
3. Cytochrome P450: Structure, Mechanism, and Biochemistry;Guengerich,2005
4. Flexibility and stability of the structure of cytochromes P450 3A4 and BM-3
5. Differences in flexibility of active sites of cytochromes P450 probed by resonance Raman and UV–Vis absorption spectroscopy
Cited by 18 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Drug–Drug Interactions Of Amiodarone And Quinidine On The Pharmacokinetics Of Eliglustat In Rats;Drug Design, Development and Therapy;2019-12
Drug–Drug Interactions Of Amiodarone And Quinidine On The Pharmacokinetics Of Eliglustat In Rats
2. β‐caryophyllene Oxide and Trans-nerolidol Affect Enzyme Activity of CYP3A4 – In Vitro and In Silico Studies;Physiological Research;2019-10-31
3. Microsecond MD simulations of human CYP2D6 wild-type and five allelic variants reveal mechanistic insights on the function;PLOS ONE;2018-08-22
4. Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners;Journal of Inorganic Biochemistry;2018-06
5. Quinidine☆;Reference Module in Biomedical Sciences;2017
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3