Structural stability of the SARS-CoV-2 main protease: Can metal ions affect function?

Author:

Kozak John J.,Gray Harry B.,Garza-López Roberto A.

Funder

NIH

Arnold and Mabel Beckman Foundation

University of California, San Francisco

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Biochemistry

Reference27 articles.

1. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors;Zhang;Science,2020

2. Fragment molecular orbital based interaction analyses on COVID-19 main protease - inhibitor N3 complex (PDB ID:6LU7);Hatada;J. Chem. Inf. Model.,2020

3. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors;Jin;Nature,2020

4. Screening of Clinically Approved and Investigation Drugs as Potential Inhibitors of COVID-19 Main Protease: A Virtual Drug Repurposing Study;Durdagi,2020

5. Rigidity, normal modes and flexible motion of a SARS-CoV-2 (COVID-19) protease structure;Wells;bioRxiv,2020

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