Interaction of 17α-hydroxylase, 17(20)-lyase (CYP17A1) inhibitors – abiraterone and galeterone – with human sterol 14α-demethylase (CYP51A1)
Author:
Funder
Russian Foundation for Basic Research
Ministry of Education and Science of the Russian Federation
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Biochemistry
Reference49 articles.
1. Substrate oxidation by cytochrome P450 enzymes;Ortiz De Montellano,2015
2. CYP17A1 inhibitors in castration-resistant prostate cancer;Gomez;Steroids,2015
3. Hits identified in library screening demonstrate selective CYP17A1 lyase inhibition;Krug;J. Steroid Biochem. Mol. Biol.,2013
4. Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001;Devore;Nature,2012
5. Specificity of antiprostate cancer CYP17A1 inhibitors on androgen biosynthesis;Udhane;Biochem. Biophys. Res. Commun.,2016
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